8 Best Moisturizer to Use with Tretinoin

A strong type of vitamin A called retinoin is highly sought after for its remarkable skin-changing properties. While its benefits for acne, fine wrinkles, and discoloration have been demonstrated, it can also irritate and dry the skin. Using the proper lotion with tretinoin is crucial to preventing these adverse effects. This article discusses the best moisturizer to use with tretinoin to maintain healthy, glowing skin.

What is Tretinoin and Its Benefits?

One prescription-only retinoid is called tretinoin, sometimes known as Retin-A. People like it because it quickens cell turnover, which makes the skin look younger, healthier, and smoother. By helping the skin to shed old cells and grow new ones, tretinoin lessens the appearance of wrinkles and fine lines and gets rid of dark spots.

Benefits of Tretinoin

Acne Treatment: Unclogging pores helps to prevent and lessen acne breakouts.

Anti-aging: Reducing fine lines and wrinkles, anti-aging stimulates collagen synthesis.

Better Texture: Encourages smoother, more equal skin tone.

Hyperpigmentation:  Lighten out skin coloring and lightens dark areas.

Even with these advantages, tretinoin can produce dryness, redness, and flaking, particularly when first used. Therefore, it is essential to use a complementary moisturizer to maintain the skin’s barrier and hydration levels.

The 8 Best Moisturizer to Use with Tretinoin

If you know which moisturizer to use with tretinoin, your skincare regimen may be revolutionized. These are the best moisturizer to use with tretinoin.

1. CeraVe Moisturizing Cream

8 Best Moisturizers to Use with Tretinoin

Key Ingredients: Ceramides, Hyaluronic Acid, Glycerin

Specialties: The skin’s natural barrier is restored and maintained best by this thick, non-greasy, quickly absorbing cream. Hyaluronic acid and ceramides moisturize and hold moisture, which is ideal for sensitive skin receiving tretinoin therapy.

2. Neutrogena Hydro Boost Water Gel

best moisturizer to use with tretinoin

Key Ingredients: Glycerin, Hyaluronic Acid

Specialties: Distinguished by its light, gel-like texture, Neutrogena Hydro Boost deeply hydrates without blocking pores. Because hyaluronic acid helps seal moisture, tretinoin-induced dry and irritated skin is soothed.

3. La Roche-Posay Toleriane Double Repair Face Moisturizer

La Roche-Posay Toleriane Double Repair Face Moisturizer

Key Ingredients: Glycerin, Prebiotic Thermal Water, Ceramide-3

Specialties: This moisturizer rebuilds the skin barrier and hydrates for 48 hours. As glycerin and ceramide-3 provide deep hydration and skin barrier restoration, niacinamide reduces irritation.

4. EltaMD PM Therapy Facial Moisturizer

best moisturizer to use with tretinoin

Key Ingredients: Hyaluronic Acid, Niacinamide, and vitamins.

Specialties: It would help if you only used this lotion at night, and it won’t clog your pores. It helps the skin’s natural layer of moisture get better and heal. Nyqualamine and hyaluronic acid also help the face heal and stay moist for a long time.

5. Aveeno Calm + Restore Oat Gel Moisturizer

best moisturizer to use with tretinoin

Key Ingredients: Oat, which is a prebiotic, and feverfew extract

Specialties: This gel moisturizer calms irritated skin and restores wetness with feverfew extract and oat prebiotics. It works exceptionally well for people with sensitive skin who are dealing with the dryness of tretinoin.

6. Vanicream Moisturizing Cream

best moisturizer to use with tretinoin

Key Ingredients: Sorbitol, Petrolatum, Glycerin

Specialties: Parabens, fragrances, and dyes are among the central irritants that Vanicream is free from. It is a basic but powerful moisturizer. For people with dryness associated with tretinoin, its thick, creamy texture offers significant hydration and helps preserve the skin barrier.

7. First Aid Beauty Ultra Repair Cream

best moisturizer to use with tretinoin

Key Ingredients: Allantoin, Shea Butter, Colloidal Oatmeal

Specialties: The formulation of this potent treatment cream is to soothe and hydrate dry, upset skin for a long time. Perfect for use with tretinoin, shea butter intensively hydrates, and colloidal oatmeal and allantoin soothe inflammation.

8. Bioderma Atoderm Intensive Baume

best moisturizer to use with tretinoin

Key Ingredients: Niacinamide, Lipigenium Complex

Specialties: Sensitive and dehydrated skin suits this incredibly nourishing balm well. Niacinamide lowers inflammation, so the Lipigenium combination is perfect for tretinoin users since it helps rebuild the skin barrier and preserve moisture.


While using tretinoin can significantly enhance your skin, it frequently has drawbacks, including dryness and inflammation. The proper moisturizer can make all the difference in keeping your skin pleasant, nourished, and safe. With their variety of formulations to meet various skin types and requirements, the eight moisturizers mentioned above are among the finest to use with tretinoin. By including one of these moisturizers in your skincare regimen, you may reduce the adverse effects of tretinoin and optimize its benefits.


What qualities in a tretinoin-compatible lotion should I search for?

  • Seek out lotions high in hyaluronic acid, glycerin, and other moisture-retaining components. Selecting products free of fragrances or other potentially irritating components is also the best way to prevent your skin from becoming even more sensitive.

I applied tretinoin; may I apply lotion immediately away?

  • Using a moisturizer immediately following tretinoin application can help lessen dryness and soreness. Some like to wait twenty to thirty minutes after applying tretinoin to moisturize because they believe it will absorb completely.

I use tretinoin; how often should I moisturize?

  • You should moisten your skin at least twice a day, in the morning and at night, to maintain optimum hydration and strengthen the skin barrier.

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